• Behandling av motoriske symptomer ved Parkinsons sykdom 

      Dietrichs, Espen; Alves, Guido Werner; Benjaminsen, Espen; Johansen, Krisztina Kunszt; Tysnes, Ole-Bjørn (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-04)
      Gjennom de siste årene har nye terapimuligheter og økt kunnskap om gamle metoder ført til endringer i vår behandling av Parkinsons sykdom. Likevel åpner alle tilgjengelige norske og utenlandske terapianbefalinger for ulike og ofte sidestilte alternativer. Basert på de evidensbaserte terapianbefalingene og på våre egne personlige erfaringer og oppfatninger presenterer vi i denne kliniske oversikten ...
    • Comorbidity in multiple sclerosis patients from Nordland County, Norway - validated data from the Norwegian Patient Registry 

      Benjaminsen, Espen; Myhr, Kjell-Morten; Torkildsen, Nina Agnethe Grytten; Alstadhaug, Karl Bjørnar (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-12-16)
      <p><i>Background:</i> Knowledge of comorbid disorders is important to optimize therapy for multiple sclerosis (MS), but data are limited. The aim of this study was to assess comorbidity in persons with MS living in Nordland County on January 1, 2017. <p><i>Methods:</i> Data were retrieved from the Norwegian Patient Registry (2008-2017) and validated through review of electronic hospital charts ...
    • Effectiveness of Natalizumab in Achieving No Evidence of Disease Activity (NEDA-3)—Data From a Local Norwegian Cohort 

      Jaklin, Andreas K.; Benjaminsen, Espen; Alstadhaug, Karl Bjørnar (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-20)
      Objective: We aimed to determine the effectiveness of natalizumab (NTZ) by assessing overall No Evidence of Disease Activity 3 (NEDA-3) in a local Norwegian cohort. <p> <p>Background: NTZ is an immunomodulating drug used in the treatment of multiple sclerosis (MS). It has typically been used as a second-line treatment, but certain patients with high disease activity have started directly with ...
    • Month of birth and risk of multiple sclerosis: confounding and adjustments 

      Torkildsen, Øivind Fredvik; Aarseth, Jan Harald; Benjaminsen, Espen; Celius, Elisabeth Gulowsen; Holmøy, Trygve; Kampman, Margitta Theodora; Løken-Amsrud, Kristin Ingeleiv; Midgard, Rune; Myhr, Kjell-Morten; Riise, Trond; Torkildsen, Nina Agnethe Grytten (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)
      A month of birth effect on multiple sclerosis (MS) risk has been reported from different countries. Recent critics have suggested that this finding is caused by confounding and that adequately adjusting for year and place of birth would markedly reduce this effect. All inhabitants in Norway are registered in the Norwegian Population Registry (Statistics Norway), making this an ideal area for performing ...
    • Multiple sclerosis in Northern Norway, epidemiology and comorbidity 

      Benjaminsen, Espen (Doctoral thesis; Doktorgradsavhandling, 2022-04-25)
      <p><i>Background:</i> Multiple sclerosis (MS) is a severe chronic inflammatory disease in the central nervous system, mainly affecting young adults. The prevalence varies between different parts of the world, but the general rule is that it increases with increasing latitude. Studies on comorbid conditions in MS are limited, but this topic have gained increasing interest. <p><i>Aims:</i> To describe ...
    • Posterior reversible encephalopathy syndrome, a clinically diverse and challenging disorder 

      Chruickshank, Therese; Thoresen, Hanne; Benjaminsen, Espen; Odeh, Francis (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-04-14)
      The characterizing features of Posterior reversible encephalopathy syndrome (PRES) are broad and diverse, making early recognition and diagnosis challenging tasks. To illustrate the heterogeneous nature of PRES, we present three cases and discuss their clinical and radiological presentation.
    • Validation of the multiple sclerosis diagnosis in the Norwegian Patient Registry 

      Benjaminsen, Espen; Myhr, Kjell-Morten; Grytten, Nina; Alstadhaug, Karl Bjørnar (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-04)
      <i>Background</i> - Health registries may yield important data for epidemiological studies. However, in order to be a valuable source for information, the registered data have to be correct.<p><p> <i>Objectives</i> - The aim of the study was to validate data from the Norwegian Patient Registry (NPR) regarding multiple sclerosis (MS).<p><p> <i>Materials and Methods</i> - We obtained data ...